Drug Sensitivity Testing
Drug Sensitivity Testing
The core of our laboratory's drug screening platform lies in mimicking the real-world interactions between drugs and human cells ex vivo. We directly utilize cell populations isolated from autologous peripheral blood as testing targets, including T cells (responsible for cellular immunity), Natural Killer (NK) cells (which immediately recognize and lyse diseased cells), Omnipotent Monocytes (OPMs, possessing multipotent repair potential), and Circulating Tumor Cells (CTCs, serving as clinical indicators for cancer metastasis monitoring).
By introducing various candidate compounds into these specific cell populations, we can precisely observe the biological effects exerted by each agent across different cell types. On one hand, we search for drug components capable of promoting growth and activation to enhance the activity of immune cells and multipotent repair cells, thereby providing technical support for cell therapy and regenerative medicine. On the other hand, we focus on screening compounds that effectively inhibit cell growth to precisely target circulating tumor cells and halt cancer dissemination. This comprehensive screening model offers crucial data support for personalized precision medicine in clinical practice.
- Nutrients: Evaluate the regulatory impacts of vitamins, minerals, and other essential nutrients on cell behavior.
- Natural Extracts: Test the health-promoting and anti-aging potential of compounds such as resveratrol and Astragalus polysaccharides.
- Cytokines: Analyze the pivotal roles of interleukins, interferons, and related molecules in immune regulation.
- Growth Factors: Assess the functional roles of various growth factors in cellular proliferation and tissue repair.
- Peptides: Test the therapeutic effects of peptides, such as thymosin and transfer factors, on cellular repair and regeneration.
- Traditional Chinese Medicine (TCM) Extracts: Evaluate the immunomodulatory effects of various herbal extracts, including Ginkgo biloba and Ginseng.
- Pharmaceuticals: Test the impact of active pharmaceuticals, such as corticosteroids and estrogens, on cell viability and immune function.
- Immunosuppressants: Establish cost-effective benchmarks to evaluate immune tolerance and cellular stress resistance.